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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL3
All Species:
22.73
Human Site:
S435
Identified Species:
41.67
UniProt:
Q8IZE3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZE3
NP_065156.5
742
82857
S435
F
T
K
N
T
D
L
S
L
E
D
S
P
M
C
Chimpanzee
Pan troglodytes
XP_513987
742
82925
S435
F
T
K
N
I
D
L
S
L
E
D
S
P
M
R
Rhesus Macaque
Macaca mulatta
XP_001096051
736
82375
S435
F
T
K
N
I
D
L
S
L
E
D
S
S
M
R
Dog
Lupus familis
XP_537198
743
82483
S435
F
T
K
T
V
N
L
S
P
E
D
S
P
P
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBQ7
735
81315
S435
F
T
K
T
S
D
L
S
P
E
G
S
P
M
H
Rat
Rattus norvegicus
Q5M9F8
807
89107
T469
S
T
R
H
R
V
L
T
S
A
F
S
R
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514536
1518
163635
S1060
F
S
K
T
A
D
F
S
P
E
A
P
T
V
F
Chicken
Gallus gallus
NP_001012613
698
77220
L415
L
K
N
N
S
S
V
L
P
I
S
G
N
A
I
Frog
Xenopus laevis
Q561M0
827
91284
R526
E
Q
A
F
K
T
I
R
S
F
L
D
K
L
E
Zebra Danio
Brachydanio rerio
NP_955951
768
85305
T436
F
T
K
S
T
E
V
T
P
E
T
S
P
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610175
683
77833
A402
G
K
T
L
R
C
M
A
D
L
V
S
I
L
G
Honey Bee
Apis mellifera
XP_001123124
613
70111
F333
D
K
T
S
S
N
L
F
S
I
S
T
F
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177952
810
89574
T447
F
P
T
K
P
S
N
T
K
E
M
L
N
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
85.5
N.A.
80.7
21.9
N.A.
31.8
61.9
21.8
51.9
N.A.
25.7
28.4
N.A.
33.5
Protein Similarity:
100
99.1
96.7
90.3
N.A.
87.7
38.5
N.A.
37.4
71.5
39
67.5
N.A.
45.9
49.7
N.A.
50.7
P-Site Identity:
100
86.6
80
60
N.A.
66.6
20
N.A.
33.3
6.6
0
46.6
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
86.6
80
66.6
N.A.
73.3
40
N.A.
46.6
20
13.3
80
N.A.
26.6
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
8
0
8
8
0
0
16
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
0
0
0
39
0
0
8
0
31
8
0
0
0
% D
% Glu:
8
0
0
0
0
8
0
0
0
62
0
0
0
0
8
% E
% Phe:
62
0
0
8
0
0
8
8
0
8
8
0
8
0
8
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
24
% H
% Ile:
0
0
0
0
16
0
8
0
0
16
0
0
8
8
8
% I
% Lys:
0
24
54
8
8
0
0
0
8
0
0
0
8
8
0
% K
% Leu:
8
0
0
8
0
0
54
8
24
8
8
8
0
16
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
8
0
0
31
0
% M
% Asn:
0
0
8
31
0
16
8
0
0
0
0
0
16
0
0
% N
% Pro:
0
8
0
0
8
0
0
0
39
0
0
8
39
8
8
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
16
0
0
8
0
0
0
0
8
0
16
% R
% Ser:
8
8
0
16
24
16
0
47
24
0
16
62
8
0
0
% S
% Thr:
0
54
24
24
16
8
0
24
0
0
8
8
8
0
8
% T
% Val:
0
0
0
0
8
8
16
0
0
0
8
0
0
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _